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Gene Expression Data
Assay Details
Assay
Reference: J:231044 Gage PJ, et al., Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7923-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5774846
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2
Detection system: Secondary antibody
Results
Specimen 5A: embryonic day 12.5 (more )
Note: littermates were used for controls; their exact genotype was not detailed
Structure Level Pattern Image Note
TS20: optic stalk Present 5A Expression is present in proximal tissue that gives rise to the optic stalk and future optic nerve head.
Specimen 5B: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: optic stalk Present 5B Expression is seen in the expected locations; there are extreme morphological changes in the mutants.
Specimen 5C: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: optic stalk Present 5C Expression is seen in the expected locations; there are extreme morphological changes in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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