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Gene Expression Data
Assay Details
Assay
Reference: J:63721 Lindahl M, et al., Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development. Mol Cell Neurosci. 2000 Jun;15(6):522-33
Assay type: RNA in situ
MGI Accession ID: MGI:5774541
Gene symbol: Gfra4
Gene name: glial cell line derived neurotrophic factor family receptor alpha 4
Probe: Gfra4 cDNA1
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 4A/B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Strong 4A/B

Specimen 4D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: limb mesenchyme Moderate Regionally restricted 4D Moderate expression was detected in the condensing mesenchyme.

Specimen 4E/F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Moderate 4E/F

Specimen 4G/H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon muscularis Moderate 4G/H
TS28: enteric ganglion Moderate 4G/H Expression was in the myenteric ganglia of the colon.

Specimen 5A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 5A Expression was highest in the hippocampus.
TS28: cerebral cortex Present 5A

Specimen 5C/D: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak Widespread 5C/D

Specimen 5F/G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Widespread 5F/G
TS28: spinal cord ventral horn Present Regionally restricted 5F/G Only some large neurons in this region show signal.

Specimen 6A/B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: ultimobranchial body Present 6A/B

Specimen 6D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: thyroid gland Present Regionally restricted 6D Expression was detected in distinct cells in the thyroid medulla.
TS26: parathyroid gland Absent 6D

Specimen 6G: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: thyroid gland Present Regionally restricted 6G Expression was detected in the thyroid parafollicular C cells.
TS28: parathyroid gland Present 6G

Specimen 7A/B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: adrenal medulla Present Clusters 7A/B

Specimen 7D/E: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: adrenal medulla Present Patchy 7D/E

Specimen 7G: postnatal day 40 (more )
Structure Level Pattern Image Note
TS28: adrenal medulla Present Widespread 7G Virtually all cells in the medulla have signal.

Specimen Table 2 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: neocortex Weak
TS20: midbrain Present Regionally restricted Expression was detected in ventral midbrain.
TS20: spinal cord Present Regionally restricted Expression was detected in ventral spinal cord.
TS20: dorsal root ganglion Weak
TS20: peripheral nervous system ganglion Weak
TS20: sympathetic ganglion Weak
TS20: thyroid gland Present Expression was detected in C cells.
TS20: lung Present
TS20: metanephros Present
TS20: liver Absent

Specimen Table 2 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: neocortex Present
TS24: spinal cord Present Regionally restricted Expression was detected in ventral spinal cord.
TS24: dorsal root ganglion Present
TS24: peripheral nervous system ganglion Present
TS24: sympathetic ganglion Present
TS24: adenohypophysis pars intermedia Strong
TS24: thyroid gland Strong Regionally restricted Expression was detected in C cells and in the ultimobranchial body.
TS24: parathyroid gland Absent
TS24: lung Present
TS24: metanephros Present
TS24: liver Absent

Specimen Table 2 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: neocortex Present
TS27: hippocampus Present
TS27: midbrain Present Regionally restricted Expression was detected in ventral midbrain.
TS27: spinal cord Present Regionally restricted Expression was detected in ventral spinal cord.
TS27: dorsal root ganglion Present
TS27: enteric ganglion Present
TS27: peripheral nervous system ganglion Present
TS27: sympathetic ganglion Present
TS27: adenohypophysis pars intermedia Strong
TS27: thyroid gland Strong Expression was detected in C cells.
TS27: parathyroid gland Weak
TS27: adrenal medulla Present
TS27: lung Weak
TS27: metanephros Weak
TS27: liver Absent
TS27: testis Present

Specimen Table 2 P20: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present
TS28: enteric ganglion Present
TS28: peripheral nervous system ganglion Present
TS28: sympathetic ganglion Present
TS28: adenohypophysis pars intermedia Strong
TS28: thyroid gland Strong Expression was detected in C cells.
TS28: parathyroid gland Strong
TS28: adrenal medulla Present
TS28: metanephros Absent
TS28: testis Present

Specimen Table 2 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: neocortex Present
TS28: hippocampus Strong
TS28: midbrain Present Regionally restricted Expression was detected in ventral midbrain.
TS28: spinal cord Present Regionally restricted Expression was detected in ventral spinal cord.
TS28: dorsal root ganglion Present
TS28: enteric ganglion Present
TS28: peripheral nervous system ganglion Present
TS28: sympathetic ganglion Present
TS28: adenohypophysis pars intermedia Strong
TS28: thyroid gland Strong Expression was detected in C cells.
TS28: parathyroid gland Strong
TS28: adrenal medulla Present
TS28: liver Absent
TS28: lung Absent
TS28: metanephros Absent
TS28: testis Present

Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars intermedia Strong
TS22: thyroid gland Present Regionally restricted Expression was detected in the ultimobranchial body.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory