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Gene Expression Data
Assay Details
Assay
Reference: J:231434 Heine U, et al., Role of transforming growth factor-beta in the development of the mouse embryo. J Cell Biol. 1987 Dec;105(6 Pt 2):2861-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5771676
Gene symbol: Tgfb1
Gene name: transforming growth factor, beta 1
Antibody: anti-CC (1-30)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: tail mesenchyme Present Regionally restricted 2A Expression is in connective tissue sheaths separating developing muscles from the subdermal mesenchyme and in fibroblasts separating individual groups of myotubes.

Specimen 3A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: embryo Present Regionally restricted 3A Expression is in many tissues.

Specimen 4A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: skeletal muscle Present Regionally restricted 4A Expression is in fibroblasts that separate the individual myotubes.
TS23: embryo mesenchyme Very strong Regionally restricted 4A Expression is in the fascia between muscsles.

Specimen 4B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: submandibular gland Present Regionally restricted 4B Expression is in the connective tissue surrounding the glandular epithelium.
TS23: submandibular gland primordium epithelium Absent 4B

Specimen 4C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: intestine Present Regionally restricted 4C Expression is in the submucosa.
TS23: intestine epithelium Absent 4C

Specimen 4D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: foot mesenchyme Strong Regionally restricted 4D Expression is in the subdermal mesenchyme and in fascia surrounding developing muscles.
TS23: foot joint Strong Regionally restricted 4D Expression is in joints between the cartilaginous bones of the digits.

Specimen 5A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cartilage Very strong Regionally restricted 5A Expression is in cartilage of the facial bones.
TS23: incisor dental papilla Very strong 5A
TS23: palatal shelf Very strong 5A
TS23: turbinate bone primordium Very strong 5A
TS23: dermis Present 5A
TS23: tongue mesenchyme Present Regionally restricted 5A Expression is in connective tissue.
TS23: incisor enamel organ Present Regionally restricted 5A Expression is in the stellate reticulum.
TS23: stellate reticulum Present 5A

Specimen 5B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: trachea mesenchyme Very strong Regionally restricted 5B Expression is in mesenchyme between tracheal cartilage and epithelium.
TS23: larynx Very strong 5B
TS23: sternum Very strong 5B

Specimen 6A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS19: somite Present 6A Expression is in the cytoplasm of individual cells that are distributed evenly throughout each somite.

Specimen 6B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord meninges Very strong 6B
TS21: sclerotome Present Regionally restricted 6B Expression is in the anterior and posterior regions.

Specimen 6C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord meninges Strong 6C
TS21: vertebral cartilage condensation Present 6C
TS21: intervertebral disc Absent 6C

Specimen 7A: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: rib Very strong 7A

Specimen 7B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: chondrocranium Very strong Regionally restricted 7B Expression is in membranous bone.

Specimen 8A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: brain meninges Strong 8A

Specimen 8B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 8B Expression is in a single layer of elongated cells overlying neural tissue.

Specimen 8C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: brain Present Regionally restricted 8C Expression is in the cytoplasm of the arachnoid endothelium and in cells of the pia mater.

Specimen 8D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: meninges Present Regionally restricted 8D Expression is in the arachnoidal endothelium (weak) and in cells of the pia mater (strong).
TS23: brain Present Diffuse 8D

Specimen 9A: embryonic day 11.0-12.0 (more )
Structure Level Pattern Image Note
TS19: endocardial cushion Present 9A , 9B Expression is in the cytoplasm.
TS19: cardiac muscle tissue Absent 9B , 9A
TS19: endocardial lining Absent 9B , 9A

Specimen 9C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: atrioventricular valve Strong 9D , 9C Staining is strong in the cytoplasm of the connective tissue of the valve.
TS23: trachea mesenchyme Present 9D , 9C

Specimen 10A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: surface ectoderm Weak Regionally restricted 10A Expression is in the mesenchyme of the dermis in the area of vibrissa formation.

Specimen 10B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dermis Very strong Regionally restricted 10B Expression is in the mesenchyme underlying the epidermis of the lower jaw.

Specimen 10C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: dermis Very strong Regionally restricted 10C Expression is in the mesenchyme of the dermis surrounding the developing hair follicles of the lower jaw.

Specimen 10D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: dermis Absent 10D

Specimen 11A: embryonic day 13.0 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS21: lower jaw mesenchyme Weak Regionally restricted 11A Expression is in the mesenchyme adjacent to the incisor primordium.

Specimen 11B: embryonic day 15.0 (more )
Note: Bell stage of tooth development.
Structure Level Pattern Image Note
TS23: stellate reticulum Strong 11B
TS23: upper jaw incisor dental papilla Strong 11B
TS23: upper jaw incisor enamel organ Strong Regionally restricted 11B Expression is in the stellate reticulum.
TS23: nasal cavity Very strong 11B
TS23: upper jaw mesenchyme Present Regionally restricted 11B Expression is in tissue surrounding the capillaries that infiltrate the developing tooth under the outer dental epithelium.

Specimen not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: tooth Present


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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory