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Gene Expression Data
Assay Details
Assay
Reference: J:25272 McConnell JE, et al., The mouse 14-3-3 epsilon isoform, a kinase regulator whose expression pattern is modulated in mesenchyme and neuronal differentiation. Dev Biol. 1995 May;169(1):218-28
Assay type: RNA in situ
MGI Accession ID: MGI:5770729
Gene symbol: Ywhae
Gene name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Probe: Ywhae cDNA
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 5a: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: gut Present Uniform 5a
TS13: neural tube Present Uniform 5a
TS13: paraxial mesenchyme Present Uniform 5a
TS13: surface ectoderm Present Uniform 5a

Specimen 5b: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: paraxial mesenchyme Strong 5b
TS15: trunk mesenchyme Strong Regionally restricted 5b Expression was strong in the lateral mesenchyme.
TS15: myotome Weak 5b
TS15: nephric duct, mesonephric portion Weak 5b
TS15: neural tube Weak 5b
TS15: surface ectoderm Weak 5b
TS15: mesonephros Weak Regionally restricted 5b A low level of expression was noted in the early mesonephric glomeruli.

Specimen 6a: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: intermediate mesenchyme Present 6a

Specimen 6b: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: metanephric mesenchyme Strong 6b
TS18: ureteric bud Absent 6b

Specimen 6c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Strong 6c

Specimen 6d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mesenchyme of metanephros Strong 6d

Specimen 7A: embryonic day 11.5 (more )
Note: Expression staining was brown; counterstain was green.
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 7A Expression was noticeably less in the ventral horn region than in the rest of the neural tube.

Specimen 7B: embryonic day 11.5 (more )
Note: Expression staining was brown; counterstain was green.
Structure Level Pattern Image Note
TS19: lung mesenchyme Strong 7B
TS19: cardiac muscle tissue Weak 7B
TS19: lung epithelium Weak 7B

Specimen 7C: embryonic day 12.5 (more )
Note: Expression staining was brown; counterstain was green.
Structure Level Pattern Image Note
TS21: mandible mesenchyme Strong 7C
TS21: tongue mesenchyme Strong 7C
TS21: tooth Present 7C

Specimen 8a/b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo mesenchyme Strong 8a/b Loose mesenchyme had the highest expression levels.
TS20: cerebral cortex Present 8a/b
TS20: dorsal root ganglion Present 8a/b
TS20: epithelium Weak 8a/b

Specimen 8c/d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Strong 8c/d The interstitial mesenchyme had a high level of expression.
TS20: lung epithelium Weak Regionally restricted 8c/d The epithelial linings of the segmental bronchioles had low expression levels.

Specimen 8e/f: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: rib pre-cartilage condensation Present Regionally restricted 8e/f Expression was detected in the intercostal mesenchyme, but there was little mRNA in the differentiating bone.

Specimen 8g/h: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: early nephron Weak 8g/h
TS20: primitive collecting duct Weak 8g/h

Specimen 8i/j: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gut mesenchyme Strong 8i/j Expression was more pronounced in the intermediate mesenchymal layer of the gut than in the inner and outer epithelial layers.
TS20: gut epithelium Weak 8i/j

Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo mesenchyme Strong
TS17: nervous system Strong
TS17: epithelium Weak
TS17: liver Trace

Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Strong
TS23: cerebral cortex Strong
TS23: dorsal root ganglion Strong
TS23: mesenchyme of metanephros Strong
TS23: spinal cord Strong
TS23: diencephalon roof plate Strong Expression was strong in the roof of the third ventricle.
TS23: bone Weak
TS23: collecting duct Weak
TS23: gut mesenchyme Weak
TS23: lung mesenchyme Weak
TS23: renal tubule Weak Regionally restricted Expression was low in the majority of nephrogenic tubules.
TS23: epithelium Trace
TS23: liver Trace
TS23: tooth Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory