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Gene Expression Data
Assay Details
Assay
Reference: J:130971 Hasegawa H, et al., Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci. 2007 Dec 26;27(52):14404-14
Assay type: RNA in situ
MGI Accession ID: MGI:5767320
Gene symbol: Avil
Gene name: advillin
Probe: Avil cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present 1A
TS22: vagus ganglion Present 1A
TS22: vestibulo-cochlear ganglion Present 1A
TS22: cerebellum Absent 1A
TS22: cerebral cortex Absent 1A
TS22: thalamus Absent 1A
Specimen 1Ba: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trigeminal ganglion Present Scattered 1Ba Expression in a few scattered cells.
Specimen 1Bb: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 1Bb Authors report expression in many cells.
Specimen 1Bc: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: facial ganglion Strong 1Bc Level of expression increases, reaching maxium level at E16.5.
TS22: trigeminal ganglion Strong 1Bc Level of expression increases, reaching maxium level at E16.5.
Specimen 1Ca: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Ambiguous 1Ca
Specimen 1Cb: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 1Cb Expression report expression is clearly detected at E12.5.
Specimen 1Cc: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 1Cc Expression increases during embryonic stages.
Specimen 1Da: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: trigeminal ganglion Strong 1Da Author report maximal expression is maintained.
Specimen 1Db: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Strong 1Db
TS27: spinal cord Absent 1Db
Specimen 1Ea/Ec: postnatal day 0 (more )
Note: Double labeled: purple - Avil; red - NeuN (Rbfox3; assay MGI:5767321).
Structure Level Pattern Image Note
TS27: trigeminal ganglion Present 1Ec , 1Ea
Specimen 1Ed/Ef: postnatal day 0 (more )
Note: Double labeled: purple - Avil; red - NeuN (Rbfox3; assay MGI:5767321).
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present 1Ef , 1Ed
Specimen E12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present Regionally restricted Expression in ~43% of trigeminal ganglion neurons.
TS20: dorsal root ganglion Present Regionally restricted Expression in ~36% dorsal root ganglion (postmitotic) neurons.
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present Regionally restricted Expression in ~87% of trigeminal ganglion neurons.
TS22: dorsal root ganglion Present Regionally restricted Expression in ~82% dorsal root ganglion neurons.
Specimen E16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trigeminal ganglion Present Regionally restricted Expression in almost all (~98%) of trigeminal ganglion neurons.
TS24: dorsal root ganglion Present Regionally restricted Expression in almost all (~94%) dorsal root ganglion neurons.
Specimen Adult not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: sensory ganglion Present Regionally restricted Authors state that expression in all somatic sensory neurons lasts into adulthood.
Specimen S1A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vestibulo-cochlear ganglion Present S1A
Specimen S1B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vestibulo-cochlear ganglion Present S1B
Specimen S1C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: facial ganglion Present S1C
Specimen S1D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: glossopharyngeal ganglion Present S1D
TS27: vagus ganglion Present S1D
Specimen S1E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: trigeminal V motor nucleus Present Regionally restricted S1E Expression in trigeminal motoneurons (Mo5).
Specimen S1F: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: trigeminal V mesencephalic nucleus Present Regionally restricted S1F Expression in proprioceptive neurons in mesencephalic trigeminal (Me5) nucleus.
Specimen S2A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present S2A
TS27: sympathetic ganglion Absent S2A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory