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Gene Expression Data
Assay Details
Assay
Reference: J:124707 Asanoma K, et al., HOP/NECC1, a novel regulator of mouse trophoblast differentiation. J Biol Chem. 2007 Aug 17;282(33):24065-74
Assay type: RNA in situ
MGI Accession ID: MGI:5766367
Gene symbol: Tpbpa
Gene name: trophoblast specific protein alpha
Probe: Tpbp probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 1C Tpbp
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: spongiotrophoblast Present
Specimen 2A +/-: embryonic day 8.5; Hopxtm1Eno/Hopx+ (more )
Structure Level Pattern Image Note
TS13: spongiotrophoblast Present 2A Tpbp HOP/NECC1+/- No differences were noted in the stained cell distribution compared to wild type.
Specimen 2A -/-: embryonic day 8.5; Hopxtm1Eno/Hopxtm1Eno (more )
Structure Level Pattern Image Note
TS13: spongiotrophoblast Present 2A Tpbp HOP/NECC1-/- No differences were noted in the stained cell distribution compared to wild type.
Specimen 2B +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 2B Tpbp HOP/NECC1+/+
Specimen 2B -/-: embryonic day 9.5; Hopxtm1Eno/Hopxtm1Eno (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Weak 2B Tpbp HOP/NECC1-/- There was a significant reduction in the number of stained cells.
Specimen 2C +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present 2C Tpbp HOP/NECC1+/+
Specimen 2C -/-: embryonic day 10.5; Hopxtm1Eno/Hopxtm1Eno (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Weak 2C Tpbp HOP/NECC1-/- There was a significant reduction in the number of stained cells.
Specimen 2D +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: spongiotrophoblast Present 2D Tpbp HOP/NECC1+/+
Specimen 2D -/-: embryonic day 11.5; Hopxtm1Eno/Hopxtm1Eno (more )
Structure Level Pattern Image Note
TS19: spongiotrophoblast Present 2D Tpbp HOP/NECC1-/- Expression reappeared in the mutant at E11.5.
TS19: trophoblast giant cell Present 2D Tpbp HOP/NECC1-/- Expression was detected in the Prl3d1-positive cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory