Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gng7tm1.1(EGFP/cre/ERT2)Wtsi
Name:	guanine nucleotide binding protein (G protein), gamma 7; EUCOMM targeted mutation 1.1, Wellcome Trust Sanger Institute
MGI ID:	MGI:5766130
Gene:	Gng7  Location: Chr10:80784463-80850742 bp, - strand  Genetic Position: Chr10, 39.72 cM

Mutant Cell Lines:	CEPD0001_1_A03, CEPD0001_1_A04, CEPD0001_1_B01, CEPD0001_1_B02, CEPD0001_1_B03, CEPD0001_1_B04, CEPD0001_1_C03, CEPD0001_1_D02, CEPD0001_1_D03, CEPD0001_1_D04, CEPD0001_1_E04, CEPD0001_1_F01, CEPD0001_1_G03, CEPD0001_1_G04, CEPD0001_1_H02, CEPD0001_1_H03, CEPD0001_1_H04, CEPD0001_5_A01, CEPD0001_5_A02, CEPD0001_5_A03, CEPD0001_5_A04, CEPD0001_5_B03, CEPD0001_5_B06, CEPD0001_5_C05, CEPD0001_5_C06, CEPD0001_5_D02, CEPD0001_5_E04, CEPD0001_5_F02, CEPD0001_5_G03, CEPD0001_5_H03, CEPD0001_5_H04, CEPD0001_5_H05, CEPD0001_5_H06
Germline Transmission:	Unknown
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	EUCOMMTOOLS

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Gng7tm1.1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gng7 (MGI:95787)   Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exon 4, and inserted into the intron between exons 3 and 4 is one FRT site, an engrailed 2 splice acceptor sequence, and an EGFP and cre/ERT2 expression cassette. A Rox flanked puromycin resistance cassette was deleted in ES cell with dre recombinase and exon 4 was deleted via cre recombinase. (J:155845)

Activity:	Tissue activity of this recombinase allele
Driver:	Gng7 (mouse) Summary of all recombinase alleles driven by Gng7. Alliance mouse Gng7 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng7 Mutation:	75 strains or lines available

Original:	J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:	1 reference(s)