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Gene Expression Data
Assay Details
Assay
Reference: J:227879 Williamson KA, et al., Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects. Am J Hum Genet. 2014 Feb 6;94(2):295-302
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5763796
Gene symbol: Yap1
Gene name: yes-associated protein 1
Antibody: anti-Yap1 (#ab65701)
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: green - Yap1; red - Pax2 (assay MGI:5763797).
Structure Level Pattern Image Note
TS17: optic stalk Present 2A
Specimen 2B: embryonic day 10.5 (more )
Note: Double labeled: green - Yap1; red - Pax2 (assay MGI:5763797).
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 2B Expression is seen in the neural retina. The inset shows a magnified view of staining in the retinal pigmented epithelium.
TS17: lens pit Present 2B
Specimen 2C: embryonic day 10.5 (more )
Note: Double labeled: green - Yap1; red - Pax2 (assay MGI:5763797).
Structure Level Pattern Image Note
TS17: lens pit Present 2C
TS17: optic cup Present Punctate 2C Expression is seen in the neural retina.
TS17: eye mesenchyme Strong 2C Expression is seen in the perioptic mesenchyme, as illustrated in the inset.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory