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Gene Expression Data
Assay Details
Assay
Reference: J:227879 Williamson KA, et al., Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects. Am J Hum Genet. 2014 Feb 6;94(2):295-302
Assay type: RNA in situ
MGI Accession ID: MGI:5763792
Gene symbol: Yap1
Gene name: yes-associated protein 1
Probe: Yap1 cDNA1
Probe preparation: Antisense RNA
Assay notes: These data were obtained using optical projection tomography (OTP).
Results
Specimen 9.5 dpc: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: central nervous system Present 2_9.5 - 3D Expression is seen in the future brainstem.
TS15: otocyst Present 2_9.5 - 3D

Specimen 9.5 dpc, sxn 1: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: eye Absent 2_9.5 section 1

Specimen 9.5 dpc, sxn 2: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present 2_9.5 section 2

Specimen 10.5 dpc: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye Present 2_10.5 - 3D

Specimen 10.5 dpc, sxn 1: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye Strong 2_10.5 section 1 Strong expression in the distal optic cup and overlying surface ectoderm.

Specimen 11.5 dpc: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: eye Present 2_11.5 - 3D
TS20: primary palate Present 2_11.5 - 3D
TS20: telencephalon Present 2_11.5 - 3D

Specimen 11.5 dpc, sxn 1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present 2_11.5 section 1
TS20: primary palate Present 2_11.5 section 1 Expression is seen in the fusing primary palate. This includes both the maxillary and frontonasal components.

Specimen 11.5 dpc, sxn 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong 2_11.5 section 2 Strong expression in the distal optic cup and overlying surface ectoderm.

Specimen 12.5 dpc: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Strong 2_12.5 - 3D Strong expression in the distal optic cup and overlying surface ectoderm.

Specimen 12.5 dpc, sxn: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Present 2_12.5 section Strong expression in the distal optic cup and overlying surface ectoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory