Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Psmb11Tn
Name:	proteasome (prosome, macropain) subunit, beta type, 11; T lymphopenia of naive population
MGI ID:	MGI:5763092
Synonyms:	Psmb11G220R
Gene:	Psmb11  Location: Chr14:54862767-54867013 bp, + strand  Genetic Position: Chr14, 27.87 cM
Alliance:	Psmb11Tn page

Strain of Origin:

C57BL/6

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A spontaneous mutation induced a G-to-A nucleotide substitution that results in the amino acid substitution of glycine with arginine at position 220 (p.G220R). (J:222872) Inheritance:    Dominant

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Psmb11 Mutation:	10 strains or lines available

Original:	J:222872 Nitta T, et al., The thymic cortical epithelium determines the TCR repertoire of IL-17-producing gammadeltaT cells. EMBO Rep. 2015 May;16(5):638-53
All:	1 reference(s)