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Gene Expression Data
Assay Details
Assay
Reference: J:221635 Canovas J, et al., The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a. J Neurosci. 2015 May 13;35(19):7552-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5762892
Gene symbol: Bcl11a
Gene name: BCL11 transcription factor A
Antibody: Bcl-11a antibody
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 15.5 (more )
Note: Double labeled: red - Ctip1 (Bcl11a); green - Sox2 (assay MGI:5762893).
Structure Level Pattern Image Note
TS23: cerebral cortex Present 1A
Specimen 1B: embryonic day 15.5 (more )
Note: Double labeled: red - Ctip1 (Bcl11a); green - Tbr2 (Eomes assay MGI:5762894).
Structure Level Pattern Image Note
TS23: cerebral cortex Present 1B
Specimen 1C: embryonic day 15.5 (more )
Note: Double labeled: red - Ctip1 (Bcl11a); green - Sox2 (assay MGI:5762893).
Structure Level Pattern Image Note
TS23: cortical plate Strong 1C Highly expressed in the cortical plate.
TS23: cerebral cortex intermediate zone Strong Regionally restricted 1C Highly expressed in migrating neurons in the intermediate zone.
TS23: cerebral cortex subventricular zone Absent 1C Completely excluded from ventricular and subventricular progenitor populations.
TS23: cerebral cortex ventricular layer Absent 1C Completely excluded from ventricular and subventricular progenitor populations.
Specimen 1D,D'': embryonic day 15.5 (more )
Note: Double labeled: red - Ctip1 (Bcl11a); green - Sox2 (assay MGI:5762893).
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Absent 1D , 1D'' Completely excluded from ventricular and subventricular progenitor populations.
TS23: cerebral cortex ventricular layer Absent 1D , 1D'' Completely excluded from ventricular and subventricular progenitor populations.
Specimen 1E,E'': embryonic day 15.5 (more )
Note: Double labeled: red - Ctip1 (Bcl11a); green - Sox2 (assay MGI:5762893).
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted 1E , 1E'' Authors report null expression in progenitor cells expressing Sox2.
Specimen 2C E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Uniform 2C 15.5 Uniform distribution of expression across the cortical plate.
Specimen 2C E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present Uniform 2C 17.5 Uniform distribution of expression across the cortical plate.
Specimen 2C P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical layer II Strong 2C P0
TS27: cortical layer III Strong 2C P0
TS27: cortical layer V Strong 2C P0
TS27: cortical layer VI Moderate 2C P0
TS27: cortical layer IV Weak 2C P0
Specimen 2C P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cortical layer II Strong 2C P3
TS27: cortical layer III Strong 2C P3
TS27: cortical layer V Strong 2C P3
TS27: cortical layer VI Moderate 2C P3
TS27: cortical layer IV Weak 2C P3
Specimen 2C P8: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 2C P8
TS28: cortical layer III Strong 2C P8
TS28: cortical layer V Strong 2C P8
TS28: cortical layer VI Moderate 2C P8
TS28: cortical layer IV Weak 2C P8
Specimen 2C P15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 2C P15
TS28: cortical layer III Strong 2C P15
TS28: cortical layer V Strong 2C P15
TS28: cortical layer VI Moderate 2C P15
TS28: cortical layer IV Weak 2C P15
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory