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Tg(Il21-cre)GLipp
Transgene Detail
Summary
Symbol: Tg(Il21-cre)GLipp
Name: transgene insertion G, Martin Lipp
MGI ID: MGI:5762613
Synonyms: IL21-Cre
Transgene: Tg(Il21-cre)GLipp  Location: unknown  
Alliance: Tg(Il21-cre)GLipp page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Il21-cre)GLipp expression driven by 1 gene
 
Mutation detailsThe transgenic vector was constructed using the RP24-291E22 BAC from CHORI containing the entire murine Il21 gene. The iCre replaced exons 1-2 of Il21 downstream of the promoter. Founder mice line G was established and maintained in breeding transgenic mice. (J:230488)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Il21 (mouse)
Summary of all recombinase alleles driven by Il21.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:230488 Wichner K, et al., Dysregulated development of IL-17- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat. FASEB J. 2016 Feb;30(2):761-74
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory