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Gene Expression Data
Assay Details
Assay
Reference: J:63083 Clarris HJ, et al., Dynamic spatiotemporal expression patterns of neurocan and phosphacan indicate diverse roles in the developing and adult mouse olfactory system. J Comp Neurol. 2000 Jul 17;423(1):99-111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5758932
Gene symbol: Ncan
Gene name: neurocan
Antibody: anti-neurocan
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen E11.5 not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: olfactory epithelium Present Regionally restricted In the olfactory neuroepithelium, expression barely detectable in perikarya of primary sensory neurons, but clearly localized to axons.

Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Present Regionally restricted 1A Expression localized to perikarya of a subpopulation of primary olfactory neurons in the olfactory epithelium.
TS20: olfactory nerve Present Regionally restricted 1A Expression in olfactory axons between olfactory epithelium and migratory mass.
TS20: olfactory migratory mass Present 1A Expression within the migratory mass, clearly distinct from the telencephalon.

Specimen 2A: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Present Regionally restricted 2A Expression in olfactory nerve fascicles in the lamina propria. Weak expression in N-CAM-expressing neuronal perikarya, deep to OMP-expressing perikarya.

Specimen 2B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present Regionally restricted 2B Expression in a markedly increased number of perikarya within a distinct layer occupying the middle one-third of the neuroepithelium.

Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Widespread 2C Expression throughout the neuroepithelium occupied by primary olfactory neurons.

Specimen 4A: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb glomerular layer Present Regionally restricted 4A Expression in primary olfactory axons forming glomeruli beneath the nerve fiber layer.

Specimen 4C: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb glomerular layer Present Regionally restricted 4C Expression in primary olfactory axons forming glomeruli beneath the nerve fiber layer.
TS26: main olfactory bulb prospective granule cell layer Present Punctate 4C
TS26: main olfactory bulb external plexiform layer Trace 4C

Specimen 4E: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb external plexiform layer Present Regionally restricted 4E Expression in the neuropil of the outer external plexiform layer. Expression in external plexiform layer is consistent with localization in apical dendrites of mitral and granule cells. No expression in perikarya of these neurons.
TS27: main olfactory bulb glomerular layer Present Diffuse 4E Authors state that diffuse expression in outer layers of the olfactory bulb made it difficult to discern individual glomeruli.

Specimen 4G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb olfactory nerve layer Present Regionally restricted 4G
TS28: main olfactory bulb glomerular layer Weak Regionally restricted 4G Weak expression in most glomeruli which were not clearly delineated.
TS28: main olfactory bulb Present Regionally restricted 4G Thin band of expression deep to the glomerular layer.

Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vomeronasal organ Present Regionally restricted Expression within perikarya of a subset of neurons.

Specimen 8A: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: vomeronasal organ Present Regionally restricted 8A Expression within perikarya of a subset of neurons. Strong expression in fascicles of axons in submucosa.

Specimen 8B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: vomeronasal organ Present Regionally restricted 8B Expression within perikarya of a subset of neurons. Strong expression in fascicles of axons in submucosa.

Specimen 8C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: vomeronasal organ Present Regionally restricted 8C Decreased expression in cell bodies of neurons. Expression continues to be present within fascicles of axons.

Specimen 8G: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: accessory olfactory bulb Present Widespread 8G
TS28: main olfactory bulb Present Widespread 8G


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory