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Gene Expression Data
Assay Details
Assay
Reference: J:39208 Sosa-Pineda B, et al., The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature. 1997 Mar 27;386(6623):399-402
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5755996
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-Glucagon
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2c: postnatal day 0; Pax4tm1Pgr/Pax4+ (more )
Note: Double labeled: brown - Gcg; blue - Pax4 reporter (assay MGI:5755864).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 2c Expression is in alpha cells at the periphery.

Specimen 2f: postnatal day 0; Pax4tm1Pgr/Pax4tm1Pgr (more )
Note: Double labeled: brown - Gcg; blue - Pax4 reporter (assay MGI:5755864).
Structure Level Pattern Image Note
TS27: pancreas Present 2f

Specimen 3b: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present 3b

Specimen 3e: embryonic day 10.5; Pax4tm1Pgr/Pax4tm1Pgr (more )
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present 3e Expression in this mutant is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory