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Gene Expression Data
Assay Details
Assay
Reference: J:166923 Wang B, et al., Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B. Hum Mol Genet. 2011 Jan 15;20(2):271-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5755274
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-Phospho-Smad1 (Ser463/465)/Smad5 (Ser463/465)/Smad9 (Ser465/467) (D5B10)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5F/G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5G , 5F Staining was only detected in the proximal region.
TS19: handplate apical ectodermal ridge Present 5F , 5G
Specimen 5H/I: embryonic day 11.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5I , 5H Staining could be detected in both the proximal and distal limb mesenchyme.
TS19: handplate apical ectodermal ridge Present 5I , 5H Increased expression compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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