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Sema3ftm2Atai
Targeted Allele Detail
Summary
Symbol: Sema3ftm2Atai
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 2, Atsu Aiba
MGI ID: MGI:5754793
Synonyms: Sema3F(loxP-neo)
Gene: Sema3f  Location: Chr9:107558699-107587674 bp, - strand  Genetic Position: Chr9, 58.91 cM, cytoband F2
Alliance: Sema3ftm2Atai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159029
Parent Cell Line:  EB3 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ cassette was inserted into exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. This allele was used to generate Sema3ftm1Atai. (J:159029)
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3f Mutation:  41 strains or lines available
Notes
ES cells = EB3, derived from E14TG2a. EB3 cells carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette.
References
Original:  J:159029 Matsuda I, et al., Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice. Neurosci Res. 2010 Mar;66(3):321-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory