Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ptger1tm1Csml
Name:	prostaglandin E receptor 1 (subtype EP1); targeted mutation 1, Clifford B Saper
MGI ID:	MGI:5753077
Synonyms:	EP1R KO
Gene:	Ptger1  Location: Chr8:84393307-84399382 bp, + strand  Genetic Position: Chr8, 40.22 cM
Alliance:	Ptger1tm1Csml page

Germline Transmission:	Earliest citation of germline transmission: J:231184
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, Null/knockout) Mutation:    Insertion   Mutation details: The targeting vector contains a loxP-flanked transcriptional blocking cassette (TBC) inserted into the first intron of gene, 497 bp upstream of the start codon. (J:231184)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptger1 Mutation:	22 strains or lines available

Original:	J:231184 Fritz M, et al., Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. J Clin Invest. 2016 Feb;126(2):695-705
All:	1 reference(s)