Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Raet1eem1Dhr
Name:	retinoic acid early transcript 1E; endonuclease-mediated mutation 1, David H Raulet
MGI ID:	MGI:5752306
Gene:	Raet1e  Location: Chr10:22034441-22059820 bp, + strand  Genetic Position: Chr10, 9.89 cM
Alliance:	Raet1eem1Dhr page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/Cas9 was used to induce a frameshift mutation in exon 2. Mutations were created in cis in both this gene and Raet1d, Raet1dem1Dhr (J:221188)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Raet1e Mutation:	13 strains or lines available

Original:	J:221188 Deng W, et al., Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science. 2015 Apr 3;348(6230):136-9
All:	2 reference(s)