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Gene Expression Data
Assay Details
Assay
Reference: J:99325 Zhao C, et al., Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region. Brain Res Dev Brain Res. 2005 Jun 9;157(1):93-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5752265
Gene symbol: Fzd9
Gene name: frizzled class receptor 9
Results
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Trace
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 1A Immunolabeling was detected broadly throughout the medial wall of the telencephalon with little or no expression laterally.
Specimen 1B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Present 1B
TS27: dentate gyrus hilus Present 1B
Specimen 1C: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 1C
TS28: dentate gyrus hilus Present 1C
Specimen 1D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 1D
TS28: dentate gyrus hilus Present 1D
Specimen 1E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 1E
Specimen 1F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Present 1F
Specimen 1G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Present 1G
Specimen 2A: embryonic day 14.5 (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 2A , 2B , 2C Expression was detected in all BrdU labeled cells in the medial cortical wall in the upper portion of the ventricular zone (B) and arrayed in closer proximity to the ventricular zone of the region that will give rise to the dentate gyrus (C).
Specimen 2D: embryonic day 14.5 (more )
Note: Double labeled: green - Fzd9; red - Nes (assay MGI:5752266).
Structure Level Pattern Image Note
TS22: telencephalon Present 2D Frizzled9 , 2D Merge There was extensive colocalization of immunolabeling with Nestin.
Specimen 3A: postnatal day 0 (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS27: dentate gyrus hilus Present 3F , 3A
TS27: hippocampal formation Present Regionally restricted 3A , 3F Expression was detected in migrating granule cells.
Specimen 3B: postnatal day 0 (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS27: hippocampal formation Present Regionally restricted 3B , 3G Expression was detected in migrating granule cells.
TS27: dentate gyrus hilus Present 3G , 3B
Specimen 3C: postnatal day 0 (more )
Note: Double labeled: green - Fzd9; red - Map2 (assay MGI:5752333).
Structure Level Pattern Image Note
TS27: dentate gyrus Present Regionally restricted 3H Merge , 3C , 3H Fzd9 Expression colocalized with Map2 in terminally differentiated neurons.
Specimen 3D: postnatal day 0 (more )
Note: Double labeled: green - Fzd9; red - Calb2 (assay MGI:5752335).
Structure Level Pattern Image Note
TS27: dentate gyrus Present Regionally restricted 3I Fzd9 , 3D , 3I Merge Expression colocalized with Calb2 in Cajal-Retzius cells in the marginal zone of the upper blade of the dentate.
Specimen 3E: postnatal day 0 (more )
Note: Double labeled: green - Fzd9; red - Gfap (assay MGI:5752338).
Structure Level Pattern Image Note
TS27: dentate gyrus Present Regionally restricted 3J Fzd9 , 3J Merge , 3E Expression colocalized with Gfap in radial glial processes in the dentate anlage.
Specimen 4A: postnatal day 8 (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Widespread 4C , 4A Expression was widely distributed in BrdU-positive cells in the hilus.
Specimen 4B: postnatal day 8 (more )
Note: Double labeled: green - Fzd9; red - Calb1 (assay MGI:5752340).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Widespread 4D , 4B
TS28: dentate gyrus granule cell layer Present 4B , 4D Expression colocalized with Calb1 in the more mature granule cells in the outer portion of the dentate granule layer.
Specimen 5A: postnatal adult (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 5A Immunolabeling was detected in the BrdU-positive cells in the subgranular zone.
Specimen 5B: postnatal adult (more )
Note: Double labeled: green - Fzd9; red - Gfap (assay MGI:5752338).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 5B Fzd9 , 5B Merge Expression was detected in Gfap-positive astrocytes in the subgranular zone.
Specimen 5C: postnatal adult (more )
Note: Double labeled: green - Fzd9; red - Calb2 (assay MGI:5752335).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5D Merge , 5C Merge , 5C Fzd9 , 5D Fzd9 Expression was detected in Calb2-positive mossy cells in the hilus.
TS28: dentate gyrus granule cell layer Present 5C Merge , 5D Merge , 5C Fzd9 , 5D Fzd9 Expression was detected in the full thickness of dentate granule neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory