Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Atoh1tm1(cre)Jbr
Name:	atonal bHLH transcription factor 1; targeted mutation 1, Jean-Francois Brunet
MGI ID:	MGI:5751764
Synonyms:	Atoh1FRTCre
Gene:	Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance:	Atoh1tm1(cre)Jbr page

Germline Transmission:	Earliest citation of germline transmission: J:229254
Parent Cell Line:	BD10 (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Conditional ready, Recombinase) Mutation:    Insertion   Atoh1tm1(cre)Jbr expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Atoh1 (MGI:104654)   Mutation details: The targeting construct inserted into the 3' UTR downstream of the stop codon an FRT-flanked neomycin resistance cassette, IRES sequence, cre recombinase gene and bovine growth hormone polyadenylation sequence. (J:229254)

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Alliance mouse Atoh1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:	36 strains or lines available

Original:	J:229254 Ruffault PL, et al., The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO(2). Elife. 2015;4
All:	2 reference(s)