Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pirbtm2Stz
Name:	paired Ig-like receptor B; targeted mutation 2, Carla J Shatz
MGI ID:	MGI:5751411
Synonyms:	PirB flox
Gene:	Pirb  Location: Chr7:3715504-3723381 bp, - strand  Genetic Position: Chr7, 2.14 cM
Alliance:	Pirbtm2Stz page

Germline Transmission:	Earliest citation of germline transmission: J:225778
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 10. An FRT and loxP site was inserted downstream of exon 13. This allele was used to generate Pirbtm2Stz. (J:225778)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pirb Mutation:	64 strains or lines available

Original:	J:225778 Bochner DN, et al., Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia. Sci Transl Med. 2014 Oct 15;6(258):258ra140
All:	3 reference(s)