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Gene Expression Data
Assay Details
Assay
Reference: J:202865 Yang T, et al., Prickle1 stunts limb growth through alteration of cell polarity and gene expression. Dev Dyn. 2013 Nov;242(11):1293-306
Assay type: RNA in situ
MGI Accession ID: MGI:5751410
Gene symbol: Wnt5a
Gene name: wingless-type MMTV integration site family, member 5A
Probe: Wnt5a probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present Regionally restricted 5E Expression in distal parts of digits.
TS20: forelimb interdigital region Absent 5E
Specimen 5F: embryonic day 12.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present Regionally restricted 5F Expression in distal parts of digits.
TS20: forelimb interdigital region Present 5F Expression in the interdigital membrane is maintained in the mutant.
TS20: forelimb digit 2 Present Regionally restricted 5F Reduced expression in the distal tip of digits 2-4 in the mutant compared with wild type.
TS20: forelimb digit 3 Present Regionally restricted 5F Reduced expression in the distal tip of digits 2-4 in the mutant compared with wild type.
TS20: forelimb digit 4 Present Regionally restricted 5F Reduced expression in the distal tip of digits 2-4 in the mutant compared with wild type.
Specimen 6G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 6G High expression in the outer half of limb bud.
Specimen 6H: embryonic day 11.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS19: handplate Weak 6H Greatly reduced expression in mutants compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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