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Gene Expression Data
Assay Details
Assay
Reference: J:161846 Westfall JE, et al., Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1. J Neurosci. 2010 Jun 30;30(26):8759-68
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5751129
Gene symbol: Ahi1
Gene name: Abelson helper integration site 1
Antibody: Ab-05/06
Detection system: Secondary antibody
Assay notes: Fixative was 1% or 4 % paraformaldehyde.
Results
Specimen 1A: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Present 1A Expression is in the transition zone of the photoreceptor sensory epithelium.
TS28: photoreceptor layer inner segment Present 1A Expression is at the edge of horizontal, bipolar, and ganglion cell bodies.
TS28: retina ganglion cell layer Present 1A Expression is at the edge of horizontal, bipolar, and ganglion cell bodies.
Specimen 1B: postnatal day 12; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Absent 1B
TS28: photoreceptor layer outer segment Absent 1B
TS28: retina ganglion cell layer Absent 1B
Specimen 1C top: postnatal day 12 (more )
Note: Double labeled: red - Ahi1; green - Rpgrip1 (assay MGI:5751147).
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Present 1C top anti-Ahi1 , 1C top merge Expression is in the transition zone of the photoreceptor sensory epithelium.
Specimen 1C bottom: postnatal day 12 (more )
Note: Double labeled: red - Ahi1; green - Rp1 (assay MGI:5751152).
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Present 1C bottom anti-Ahi1 , 1C bottom merge Expression is in the transition zone of the photoreceptor sensory epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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