Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Kittm1(cre/ERT2)Bzsh
Name:	KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Bin Zhou
MGI ID:	MGI:5750790
Synonyms:	Kit-CreER
Gene:	Kit  Location: Chr5:75735647-75817382 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance:	Kittm1(cre/ERT2)Bzsh page

Germline Transmission:	Earliest citation of germline transmission: J:228761
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Kittm1(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Kit (MGI:96677)   Mutation details: An inducible cre recombinase gene (cre/ERT2) and an FRT-flanked neomycin resistance cassette were inserted at the translation initiation site. (J:228761)

Activity:	Tissue activity of this recombinase allele
Driver:	Kit (mouse) Summary of all recombinase alleles driven by Kit. Comparative matrix view of recombinase activities Alliance mouse Kit gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kit Mutation:	179 strains or lines available

Original:	J:228761 Liu Q, et al., c-kit(+) cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair. Nat Med. 2015 Aug;21(8):866-8
All:	9 reference(s)