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Gene Expression Data
Assay Details
Assay
Reference: J:196597 Yamamoto-Shiraishi Y, et al., Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor. Dev Biol. 2013 May 15;377(2):363-74
Assay type: RNA in situ
MGI Accession ID: MGI:5750052
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Results
Specimen S8 10.75 dpc dorsal: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present S8_10.75 dpc dorsal
Specimen S8 10.75 dpc ventral: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present S8_10.75 dpc ventral
Specimen S8 11.0 dpc dorsal: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted S8_11.0 dpc dorsal Authors state expression expanded from posterior to anterior on both dorsal and ventral sides.
Specimen S8 11.0 dpc ventral: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted S8_11.0 dpc ventral Authors state expression expanded from posterior to anterior on both dorsal and ventral sides.
Specimen S8 11.5 dpc dorsal: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted S8_11.5 dpc dorsal Authors state expression expanded from posterior to anterior on both dorsal and ventral sides.
Specimen S8 11.5 dpc ventral: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted S8_11.5 dpc ventral Authors state expression expanded from posterior to anterior on both dorsal and ventral sides.
Specimen 8A Hoxa-13+/+;HoxD+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8A Hoxa-13+/+;HoxD+/+
Specimen 8A Hoxa-13+/-;HoxDdel/del: embryonic day 11.5; Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu, Hoxa13tm1Ipc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8A Hoxa-13+/-;HoxDdel/del Expression not affected compared with wildtype embryos.
Specimen 8A Hoxa-13-/-;HoxD+/del: embryonic day 11.5; Del(2Hoxd11-Hoxd13)29Ddu/+, Hoxa13tm1Ipc/Hoxa13tm1Ipc (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8A Hoxa-13-/-;HoxD+/del Expression not affected compared with wildtype embryos.
Specimen 8A Hoxa-13-/-;HoxDdel/del: embryonic day 11.5; Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu, Hoxa13tm1Ipc/Hoxa13tm1Ipc (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8A Hox-a13-/-;HoxDdel/del No expression on dorsal side.
Specimen 8B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8B
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 8C No expression on dorsal side. Ventral expression was not significantly affected.
Specimen S9 Hoxa-13+/+;HoxD+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: face Present S9_Hoxa-13+/+;HoxD+/+
Specimen S9 Hoxa-13-/-;HoxDdel/del: embryonic day 11.5; Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu, Hoxa13tm1Ipc/Hoxa13tm1Ipc (more )
Structure Level Pattern Image Note
TS19: face Present S9_Hoxa-13-/-;HoxDdel/del Expression was not distinguishable from that of wildtype embryos.
Specimen S11 mouse forelimb Six2: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted S11_mouse forelimb Six2 Expression in mesenchyme of posterior distal limb bud.
Specimen S11 mouse hindlimb Six2: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted S11_mouse hindlimb Six2 Expression in mesenchyme of posterior distal limb bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory