Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(CAG-cre/ERT2/Hif1a)#Hhas
Name:	transgene insertion, Hesham A Sadek
MGI ID:	MGI:5749962
Synonyms:	CAG-creERT2-ODD
Transgene:	Tg(CAG-cre/ERT2/Hif1a)#Hhas  Location: unknown
Alliance:	Tg(CAG-cre/ERT2/Hif1a)#Hhas page

Strain of Origin:

C57BL/6 x C3H

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen and hypoxia Mutation:    Insertion   Tg(CAG-cre/ERT2/Hif1a)#Hhas expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note chicken CAG   Mutation details: The transgene contains the CAG promoter drives ubiquitous expression of the inducible cre recombinase gene (cre/ERT2) fused with the oxygen-dependent degradation (ODD) domain of Hif1a. This transgene is responsive to hypoxia. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:224072)

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:224072 Kimura W, et al., Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature. 2015 Jul 9;523(7559):226-30
All:	3 reference(s)