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Gene Expression Data
Assay Details
Assay
Reference: J:228711 Lanctot C, et al., Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development. Endocrinology. 1999 Mar;140(3):1416-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5749787
Gene symbol: Pomc
Gene name: pro-opiomelanocortin-alpha
Antibody: Anti-ACTH
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 4G: postnatal adult (more )
Note: Double labeled: blue - Pomc; brown - Pitx1 (assay MGI:5749652).
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Present 4G Expression was detected in corticotrophs. A fraction of expressing cells also had high levels of Pitx1.
Specimen 4K: embryonic day 16.5 (more )
Note: Double labeled: blue - Pomc; brown - Pitx1 (assay MGI:5749652).
Structure Level Pattern Image Note
TS24: pituitary gland Present 4K Immunopositive corticotrophs were found that co-expressed Pitx1 at both high and low levels. Those immunopositive corticotrophs that co-expressed high levels of Pitx1 were mostly found in the ventral region of the gland.
Specimen 4L: embryonic day 16.5 (more )
Note: Double labeled: blue - Pomc; brown - Pitx1 (assay MGI:5749652).
Structure Level Pattern Image Note
TS24: pituitary gland Present 4L Immunopositive corticotrophs were found that co-expressed Pitx1 at both high and low levels. Those immunopositive corticotrophs that co-expressed high levels of Pitx1 were mostly found in the ventral region of the gland.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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