Tg(tetO-Pou4f2,-Isl1)1Xmu
Transgene Detail
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| Symbol: |
Tg(tetO-Pou4f2,-Isl1)1Xmu |
| Name: |
transgene insertion 1, Xiuqian Mu |
| MGI ID: |
MGI:5749713 |
| Synonyms: |
tetO-P&I |
| Transgene: |
Tg(tetO-Pou4f2,-Isl1)1Xmu Location: unknown
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| Alliance: |
Tg(tetO-Pou4f2,-Isl1)1Xmu page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Conditional ready, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO-Pou4f2,-Isl1)1Xmu expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| Not Specified |
Isl1 |
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| Not Specified |
Pou4f2 |
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Mutation details: A construct consisting of a tetO promoter, lox2272 site, loxP site, Pou4f2 cDNA, T2A self-cleaving peptide, Isl1 cDNA, polA sequence, lox2272 site, Pou4f2 cDNA, polyA sequence, loxP site, Isl1 cDNA, FRT site and polyA sequence was inserted. Two lines were produced, but only the one responsive to tTA was used in J:220735.
(J:220735)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:220735 Wu F, et al., Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1559-68 |
| All: |
2 reference(s) |
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Analysis Tools
