Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Angpt1tm2.1Sjm
Name:	angiopoietin 1; targeted mutation 2.1, Sean J Morrison
MGI ID:	MGI:5749674
Synonyms:	Angpt1fl
Gene:	Angpt1  Location: Chr15:42288119-42540373 bp, - strand  Genetic Position: Chr15, 16.69 cM
Alliance:	Angpt1tm2.1Sjm page

Germline Transmission:	Earliest citation of germline transmission: J:220459
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: An FRT flanked neo cassette and loxP site were inserted upstream of exon 1 and a loxP site was inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:220459)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Angpt1 Mutation:	35 strains or lines available

Original:	J:220459 Zhou BO, et al., Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1. Elife. 2015;4
All:	3 reference(s)