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Gene Expression Data
Assay Details
Assay
Reference: J:128922 Zheng-Fischhofer Q, et al., Characterization of connexin31.1-deficient mice reveals impaired placental development. Dev Biol. 2007 Dec 1;312(1):258-71
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5749422
Gene symbol: Gjb5
Gene name: gap junction protein, beta 5
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 2.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Note: Morula stage embryo.
Structure Level Pattern Image Note
TS4: compacted morula Absent 2A

Specimen 2B: embryonic day 3.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Note: Blastocyst stage embryo.
Structure Level Pattern Image Note
TS5: inner cell mass Absent 2B

Specimen 2C: embryonic day 6.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Present 2C
TS9: extraembryonic ectoderm Present 2C
TS9: trophectoderm Present 2C
TS9: embryo Absent 2C

Specimen 2D: embryonic day 8.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present 2D
TS13: trophectoderm Present 2D
TS13: embryo Absent 2D

Specimen 2F: embryonic day 9.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 2F
TS15: spongiotrophoblast Present 2F
TS15: syncytiotrophoblast Absent 2F
TS15: trophoblast giant cell Absent 2F

Specimen 2G: embryonic day 11.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS19: spongiotrophoblast Trace 2G
TS19: trophectoderm Present Regionally restricted 2G Expression is in placental glycogen cells.

Specimen 2H: postnatal adult; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Note: E15.5 placenta.
Structure Level Pattern Image Note
TS28: placenta Present Regionally restricted 2H Expression is in placental glycogen cells.

Specimen 2I: postnatal adult; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Note: E15.5 placenta.
Structure Level Pattern Image Note
TS28: placenta Present Regionally restricted 2I Expression is in placental glycogen cells.

Specimen 3A: embryonic day 13.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS21: nasal cavity epithelium Strong 3A
TS21: vomeronasal organ Strong 3A
TS21: midbrain mantle layer Present 3A
TS21: trigeminal nerve Present 3A

Specimen 3B: embryonic day 15.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS23: epidermis Present Single cells 3B Expression is in keratinocytes.

Specimen 3C: embryonic day 13.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS21: nasal cavity epithelium Strong 3C
TS21: vomeronasal organ Strong 3C

Specimen 3D: embryonic day 13.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS21: midbrain mantle layer Present 3D

Specimen 3E: embryonic day 13.5; Gjb5tm1Kwi/Gjb5tm1Kwi (more )
Structure Level Pattern Image Note
TS21: trigeminal nerve Present 3E

Specimen 4A: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 4A Expression is in suprabasal layers.
TS28: epidermis cornified layer Present 4A
TS28: epidermis granular layer Present 4A
TS28: epidermis spinous layer Present 4A
TS28: epidermis basal layer Absent 4A

Specimen 5A: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Strong Regionally restricted 5A Expression is in subregions of the olfactory epithelium located in the dorsal zone of the nose and additional staining at the tip of the endoturbinates II and III and on ectoturbinate 2.

Specimen 5B: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 5B Expression is in the dorsal zone of the olfactory epithelium located adjacent to the olfactory bulb.
TS28: main olfactory bulb Absent 5B
TS28: nasal cavity respiratory epithelium Absent 5B

Specimen 5C: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 5C Expression is in the layer of olfactory sensory cells. Absent in the sustentacular cells.
TS28: nasal cavity lamina propria Absent 5C

Specimen 5D: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: vomeronasal organ sensory epithelium Present 5D Expression is in the apical layer of the sensory epithelium close to the lumen.
TS28: vomeronasal organ non-sensory epithelium Absent 5D

Specimen not shown A: postnatal adult; Gjb5tm1Kwi/Gjb5+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present
TS28: sebaceous gland Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory