Dhrs7btm1.1Sem
Targeted Allele Detail
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| Symbol: |
Dhrs7btm1.1Sem |
| Name: |
dehydrogenase/reductase 7B; targeted mutation 1.1, Clay F Semenkovich |
| MGI ID: |
MGI:5749209 |
| Synonyms: |
PexRAP |
| Gene: |
Dhrs7b Location: Chr11:60721457-60749249 bp, + strand Genetic Position: Chr11, 37.87 cM
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| Alliance: |
Dhrs7btm1.1Sem page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:219976
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: An FRT flanked construct containing splice acceptor site, beta-gal, neo and polyA sequences and loxP site were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. The targeting vector (design ID 39122) was obtained from the EUCOMM repository. Flp mediated recombination removed the beta-gal, neo construct.
(J:219976)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Dhrs7b Mutation: |
104 strains or lines available
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| Original: |
J:219976 Lodhi IJ, et al., Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability. Cell Metab. 2015 Jan 6;21(1):51-64 |
| All: |
3 reference(s) |
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Analysis Tools
