Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ubtftm1.1Tmss
Name:	upstream binding transcription factor, RNA polymerase I; targeted mutation 1.1, Tom Moss
MGI ID:	MGI:5708602
Synonyms:	Ubffl
Gene:	Ubtf  Location: Chr11:102195386-102210568 bp, - strand  Genetic Position: Chr11, 66.29 cM, cytoband D
Alliance:	Ubtftm1.1Tmss page

Germline Transmission:	Earliest citation of germline transmission: J:228597
Parent Cell Line:	WW6 (ES Cell)
Strain of Origin:	STOCK 129/Sv and C57BL/6J and SJL

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exons 3 through 5 floxed. (J:228597)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ubtf Mutation:	55 strains or lines available

Original:	J:228597 Hamdane N, et al., Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body. PLoS Genet. 2014 Aug;10(8):e1004505
All:	5 reference(s)