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Gene Expression Data
Assay Details
Assay
Reference: J:35634 Marcinkiewicz M, et al., Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4922-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5707154
Gene symbol: Pcsk2
Gene name: proprotein convertase subtilisin/kexin type 2
Antibody: AbC mPC2
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 5A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Weak 5A

Specimen 5B: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Present 5B Expression increases during prenatal and postnatal periods.
TS26: adenohypophysis pars anterior Trace 5B Very little expression on days E18 through P3.

Specimen 5C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Present 5C Expression increases during prenatal and postnatal periods.
TS27: adenohypophysis pars anterior Weak 5C Very little expression on days E18 through P3.

Specimen 5D: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Present 5D Expression increases during prenatal and postnatal periods.
TS27: adenohypophysis pars anterior Weak 5D Expression clearly appears starting on days P3-P14.

Specimen 5E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Present 5E Expression increases during prenatal and postnatal periods.
TS28: adenohypophysis pars anterior Present 5E Expression clearly appears starting on days P3-P14.

Specimen 5F: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Present 5F Expression increases during prenatal and postnatal periods.
TS28: adenohypophysis pars anterior Strong 5F Maximal expression at P11.

Specimen 5G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Strong 5G Expression reaches a plateau at adulthood.
TS28: adenohypophysis pars anterior Present Regionally restricted 5G Expression decreases toward adulthood. Authors report expression in Acth (alphaMSH, POMC))-expressing cells.

Specimen 5I: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Weak Regionally restricted 5I Authors report expression in alphaMSH (Acth)-expressing cells.

Specimen Table 1 E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future neurohypophysis Absent

Specimen Table 1 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Absent
TS20: adenohypophysis pars intermedia Absent

Specimen Table 1 E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: adenohypophysis pars anterior Absent
TS21: adenohypophysis pars intermedia Absent

Specimen Table 1 E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Absent
TS22: adenohypophysis pars intermedia Absent

Specimen Table 1 E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: adenohypophysis pars anterior Absent
TS23: adenohypophysis pars intermedia Absent

Specimen Table 1 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Trace
TS24: adenohypophysis pars anterior Absent

Specimen Table 1 E17: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: adenohypophysis pars intermedia Weak
TS25: adenohypophysis pars anterior Ambiguous

Specimen Table 1 E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Weak
TS26: adenohypophysis pars anterior Ambiguous

Specimen Table 1 E20: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Weak
TS26: adenohypophysis pars anterior Absent

Specimen Table 1 P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Present
TS27: adenohypophysis pars anterior Absent

Specimen Table 1 P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars anterior Trace
TS27: adenohypophysis pars intermedia Present

Specimen Table 1 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Weak
TS28: adenohypophysis pars intermedia Present

Specimen Table 1 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Weak
TS28: adenohypophysis pars intermedia Present

Specimen Table 1 P9: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Present
TS28: adenohypophysis pars intermedia Present

Specimen Table 1 P11: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Strong
TS28: adenohypophysis pars intermedia Strong

Specimen Table 1 P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Strong
TS28: adenohypophysis pars anterior Present

Specimen Table 1 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Very strong
TS28: adenohypophysis pars anterior Trace


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory