About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:35634 Marcinkiewicz M, et al., Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4922-6
Assay type: RNA in situ
MGI Accession ID: MGI:5707079
Gene symbol: Pcsk1
Gene name: proprotein convertase subtilisin/kexin type 1
Probe: mPC1 probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: adenohypophysis pars anterior Present Regionally restricted 1A/A' Expression on the ventral aspect of the primordium of the anterior pituitary.

Specimen 1B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars anterior Present 1B/B' Authors state intensity of expression varied little between E16 and E17.

Specimen 1C: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: adenohypophysis pars anterior Present 1C/C' Authors state intensity of expression varied little between E16 and E17.

Specimen 1D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars anterior Present 1D/D' From E18, expression increased consistently until adulthood.
TS26: adenohypophysis pars intermedia Ambiguous 1D/D' Authors state that expression is visible after E18.

Specimen 1E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars anterior Present 1E/E' From E18, expression increased consistently until adulthood.
TS27: adenohypophysis pars intermedia Present 1E/E' Expression visible after E18.

Specimen 1F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Present 1F/F' From E18, expression increased consistently until adulthood.
TS28: adenohypophysis pars intermedia Present 1F/F' Expression visible after E18.

Specimen Table 1 E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: future neurohypophysis Absent

Specimen Table 1 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Absent
TS20: adenohypophysis pars intermedia Absent

Specimen Table 1 E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: adenohypophysis pars anterior Absent
TS21: adenohypophysis pars intermedia Absent

Specimen Table 1 E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Absent
TS22: adenohypophysis pars intermedia Absent

Specimen Table 1 E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: adenohypophysis pars intermedia Absent
TS23: adenohypophysis pars anterior Trace

Specimen Table 1 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Absent
TS24: adenohypophysis pars anterior Trace

Specimen Table 1 E17: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: adenohypophysis pars intermedia Absent
TS25: adenohypophysis pars anterior Weak

Specimen Table 1 E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Ambiguous
TS26: adenohypophysis pars anterior Weak

Specimen Table 1 E20: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars intermedia Trace
TS26: adenohypophysis pars anterior Weak

Specimen Table 1 P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Weak
TS27: adenohypophysis pars anterior Weak

Specimen Table 1 P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: adenohypophysis pars anterior Present

Specimen Table 1 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Weak

Specimen Table 1 P9: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Present

Specimen Table 1 P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Weak

Specimen Table 1 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars intermedia Present
TS28: adenohypophysis pars anterior Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory