Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Cdk2tm2.1Sgo
Name:	cyclin dependent kinase 2; targeted mutation 2.1, Sagrario Ortega
MGI ID:	MGI:5706943
Synonyms:	Cdk2lox
Gene:	Cdk2  Location: Chr10:128533808-128540900 bp, - strand  Genetic Position: Chr10, 77.13 cM, cytoband D3
Alliance:	Cdk2tm2.1Sgo page

Germline Transmission:	Earliest citation of germline transmission: J:125217
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: Exons 2 and 3 are flanked by loxP sites. This allele was derived from Cdk2tm2Sgo by Cre recombinase-mediated excision of a loxP-flanked neomycin resistance gene in the third intron. (J:85230)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdk2 Mutation:	17 strains or lines available

Original:	J:85230 Ortega S, et al., Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet. 2003 Sep;35(1):25-31
All:	9 reference(s)