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Tg(Ggt1-tTA)#Agoc
Transgene Detail
Summary
Symbol: Tg(Ggt1-tTA)#Agoc
Name: transgene insertion, Adolf Garcia-Ocana
MGI ID: MGI:5705528
Synonyms: GGT-tTA
Transgene: Tg(Ggt1-tTA)#Agoc  Location: unknown  
Alliance: Tg(Ggt1-tTA)#Agoc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe kidney-specific rat gamma-glutamyl transferase gene promoter drives the expression of the tetracycline transactivating gene (tTA). Two lines were generated (1 and 2), however the pound (#) symbol is used because the data are pooled. (J:130310)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Phenotypic Similarity to Human Syndrome: Renal Cell Carcinoma J:222943.
References
Original:  J:130310 Fiaschi-Taesch NM, et al., Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor. J Am Soc Nephrol. 2004 Jan;15(1):112-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory