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Gene Expression Data
Assay Details
Assay
Reference: J:68160 Luukko K, et al., Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling. Mech Dev. 2001 Mar;101(1-2):209-12
Assay type: RNA in situ
MGI Accession ID: MGI:5705259
Gene symbol: Smad6
Gene name: SMAD family member 6
Probe: Smad6 cDNA3
Probe preparation: Antisense RNA
Results
Specimen 1D: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: heart Strong Regionally restricted 1D Expression is in the atrioventricular cushion tissue.
TS14: dorsal aorta Strong 1D
TS14: arterial system Strong Regionally restricted 1D Expression is in major arteries.
Specimen 2E: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Strong 2E
TS20: dorsal aorta Strong 2E
TS20: arterial system Strong Regionally restricted 2E Expression is in major arteries.
TS20: choroid plexus Present 2E
TS20: pituitary gland Present 2E
TS20: inner ear Present Regionally restricted 2E Expression is in the otic vesicle.
Specimen 3B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: atrioventricular endocardial cushion Present 3B
TS22: dorsal aorta Present 3B
TS22: metanephros Present 3B
TS22: urogenital sinus Present 3B
TS22: arterial system Present Regionally restricted 3B Expression is in major arteries.
TS22: mesonephros Absent 3B
Specimen 4A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: trigeminal ganglion Present Regionally restricted 4A Smad6 Expression is in a small number of cells.
TS23: primary palate Present Regionally restricted 4A Smad6 Expression is in intramembranous bones.
Specimen 4B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: mandible Present Regionally restricted 4B Smad6 Expression is in intramembranous bones.
Specimen 4C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: midgut epithelium Present 4C Smad6
Specimen 4D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: mesorchium Present 4D Smad6
TS21: male reproductive system Strong Regionally restricted 4D Smad6 Expression is in the mesenchyme around the Mullerian duct.
TS21: nephric duct Absent 4D Smad6
Specimen not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory