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Gene Expression Data
Assay Details
Assay
Reference: J:68160 Luukko K, et al., Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling. Mech Dev. 2001 Mar;101(1-2):209-12
Assay type: RNA in situ
MGI Accession ID: MGI:5705118
Gene symbol: Smad3
Gene name: SMAD family member 3
Probe: Smad3 cDNA4
Probe preparation: Antisense RNA
Results
Specimen 1B: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: nervous system Present Ubiquitous 1B
Specimen 1E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: branchial arch Strong 1E
TS16: future hindbrain Present Regionally restricted 1E Expression is in the myelencephalon.
TS16: future brain marginal layer Weak 1E
TS16: neural tube lateral wall Weak Regionally restricted 1E Expression is in the marginal layer.
Specimen 2B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: nasal cavity epithelium Strong 2B
TS20: oral epithelium Strong 2B
TS20: spinal cord floor plate Strong 2B
TS20: diencephalon Present Regionally restricted 2B Expression is in the neuroepithelium lining the brain ventricles.
TS20: hindbrain Present Regionally restricted 2B Expression is in the neuroepithelium lining the brain ventricles.
TS20: telencephalon Present Regionally restricted 2B Expression is in the neuroepithelium lining the brain ventricles.
TS20: spinal cord ventricular layer Present Regionally restricted 2B Expression is in the neuroepithelium lining the lumen of the spinal cord.
TS20: duodenum caudal part epithelium Present 2B
TS20: duodenum rostral part epithelium Present 2B
TS20: epithelial layer of ureter Present 2B
TS20: lung epithelium Present 2B
Specimen 3A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: bone Present 3A
TS22: submandibular gland primordium Present 3A
Specimen 4A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: trigeminal ganglion Weak 4A Smad3 Low or undetectable expression.
Specimen 4B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: mandible Present Regionally restricted 4B Smad3 Expression is in intramembranous bones.
Specimen 4C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: midgut Present 4C Smad3
Specimen 4D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: testis Present Ubiquitous 4D Smad3
Specimen not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: central nervous system Trace
TS23: ganglion Weak Regionally restricted Low or undetetcable expression in peripheral ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory