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Gene Expression Data
Assay Details
Assay
Reference: J:48620 Hsu LJ, et al., Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development. J Neurochem. 1998 Jul;71(1):338-44
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5704511
Gene symbol: Snca
Gene name: synuclein, alpha
Antibody: anti-NACP
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Antibody detects both Snca and Sncb.
Results
Specimen 5a: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: telencephalon Weak 5a
Specimen 5b: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present 5b
TS23: cortical plate Present 5b
TS23: cortical subplate Absent 5b
Specimen 5c: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present 5c
TS26: cortical plate Present 5c
TS26: cortical subplate Absent 5c
Specimen 5d: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Moderate 5d Expression is more prominent in pre-synaptic terminals and weaker in neuronal cell bodies.
Specimen 5e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Punctate 5e Expression is in pre-synaptic terminals and is absent in neuronal cell bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory