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Gene Expression Data
Assay Details
Assay
Reference: J:171387 Zhang H, et al., Novel discovery of LYVE-1 expression in the hyaloid vascular system. Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6157-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5704112
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: anti-LYVE-1
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3A,C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hyaloid cavity Present Regionally restricted 3A LYVE-1 , 3A Merged , 3C (left) Expression in cells that did not express CD31 (Pecam1), but some appeared to be abutting CD1-positive cells.

Specimen 3B,C: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: hyaloid cavity Present Regionally restricted 3B Merged , 3C (right) , 3B LYVE-1 Expression in cells that did not express CD31 (Pecam1), but some appeared to be linearly arranged along the CD31-positive vasculature.

Specimen 4: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: hyaloid vascular plexus Present Regionally restricted 4 Expression in cells that attached to the hyaloid vasculatures.

Specimen 5A,C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hyaloid cavity Present Regionally restricted 5A LYVE-1 , 5C (left) , 5A Merged Authors report co-expression with F4/80 (Adgre1).

Specimen 5B,C: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: hyaloid cavity Present Regionally restricted 5B Merged , 5B LYVE-1 , 5C (right) Authors report co-expression with F4/80 (Adgre1).

Specimen 6A Knockout: postnatal day 14; Angpt2tm1Gdy/Angpt2tm1Gdy (more )
Structure Level Pattern Image Note
TS28: hyaloid vascular plexus Present Regionally restricted 6A Knockout Expression in remnant hyaloid vasculatures.

Specimen 6B Control: postnatal day 14; Angpt2tm1Gdy/Angpt2+ (more )
Structure Level Pattern Image Note
TS28: hyaloid cavity Absent 6B Control


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory