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Gene Expression Data
Assay Details
Assay
Reference: J:66790 Anderson SA, et al., Distinct cortical migrations from the medial and lateral ganglionic eminences. Development. 2001 Feb;128(3):353-63
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5703075
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Antibody: anti-DLX1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4J: embryonic day 16.5 (more )
Note: Vibratome section. Double labeled: green - Dlx1; red - Pcna (assay MGI:5703074).
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 4J Greatly increased expression in the cortical proliferative zone near the striatopallial angle, primarily in the location of the subventricular zone. These cells were not mitotically active, based on their lack of PCNA expression.
TS24: cerebral cortex subventricular zone Present 4J

Specimen 4K: postnatal day 0 (more )
Note: Vibratome section. Double labeled: green - Dlx1; red - Pcna (assay MGI:5703074).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 4K Increased expression in the cortical proliferative zone. Many of these cells were proliferating, based on their expression of PCNA.

Specimen 4L: embryonic day 16.5 (more )
Note: Vibratome section. Double labeled: green - Dlx1; red - Tubb3 (assay MGI:5703076).
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 4L Greatly increased expression in the cortical proliferative zone near the striatopallial angle. These cells coexpressed Tubb3 (immature neurons).

Specimen not shown: embryonic day 14.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted Expressed in a few cells in the cortical proliferative zone near the striatopallial angle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory