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Gene Expression Data
Assay Details
Assay
Reference: J:82310 Marin O, et al., Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Development. 2003 May;130(9):1889-901
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5702674
Gene symbol: Chat
Gene name: choline O-acetyltransferase
Antibody: Anti-Chat
Results
Specimen 9A: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: preoptic area Absent 9A , 9C
TS27: anterior commissure Absent 9A
TS27: corpus striatum Present Regionally restricted 9D , 9A Expression was detected in cholinergic neurons.
TS27: basal magnocellular complex Present 9A , 9G
Specimen 9B: postnatal newborn; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS27: preoptic area Present Regionally restricted 9B , 9E Ectopic neurons are noted close to the midline in the mutant. Some cells and fibers cross the midline.
TS27: anterior commissure Present Regionally restricted 9B Ectopic cells are present in the anterior commissure in the mutant.
TS27: corpus striatum Present Regionally restricted 9B , 9F The number of cholinergic neurons within the striatum was similar in control and double mutant mice.
TS27: basal magnocellular complex Present 9I , 9B The number of cholinergic neurons was reduced in the double mutant basal magnocellular complex.
Specimen 9H: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: basal magnocellular complex Present 9H
Specimen 9J: postnatal newborn; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS27: basal magnocellular complex Present 9J The number of cholinergic neurons was reduced in the double mutant basal magnocellular complex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory