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Gene Expression Data
Assay Details
Assay
Reference: J:192889 Norden J, et al., Partial absence of pleuropericardial membranes in Tbx18- and Wt1-deficient mice. PLoS One. 2012;7(9):e45100
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5702307
Gene symbol: Tbx18
Gene name: T-box18
Reporter: GFP
Probe: GFP probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 10.5; Tbx18tm2Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 4A
TS17: visceral pericardium Present 4A
TS17: intraembryonic coelom Present Regionally restricted 4A Expression is in the parietal layer of the serous membrane lining the wall of the thoracic cavity and in the pleuropericardial membranes.
TS17: sinus venosus Present Regionally restricted 4A Expression is in the sinus horn mesenchyme.
Specimen 4B: embryonic day 11.5; Tbx18tm2Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS19: heart Strong Regionally restricted 4B Expression is in the mesenchymal ridges at the border between the sinus horns, the atria, and the pericardioperitoneal canal.
TS19: cardiac muscle tissue Present 4B
TS19: visceral pericardium Present 4B
TS19: intraembryonic coelom Present Regionally restricted 4B Expression is in the parietal layer of the serous membrane lining the wall of the thoracic cavity and in the pleuropericardial membranes.
TS19: sinus venosus Present Regionally restricted 4B Expression is in the sinus horn mesenchyme.
Specimen 4C: embryonic day 12.5; Tbx18tm2Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS20: heart Strong Regionally restricted 4C Expression is in the mesenchymal ridges at the border between the sinus horns, the atria, and the pericardioperitoneal canal.
TS20: cardiac muscle tissue Present 4C
TS20: visceral pericardium Present 4C
TS20: intraembryonic coelom Present Regionally restricted 4C Expression is in the parietal layer of the serous membrane lining the wall of the thoracic cavity and in the pleuropericardial membranes.
TS20: sinus venosus Present Regionally restricted 4C Expression is in the sinus horn mesenchyme.
Specimen 4D: embryonic day 13.5; Tbx18tm2Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS21: cardiac muscle tissue Present 4D
TS21: visceral pericardium Present 4D
TS21: intraembryonic coelom Present Regionally restricted 4D Expression is in the parietal layer of the serous membrane lining the wall of the thoracic cavity and in the pleuropericardial membranes.
TS21: heart Present Regionally restricted 4D Expression is in the sinus horn mesenchyme.
Specimen 4E: embryonic day 14.5; Tbx18tm2Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Present 4E
TS22: visceral pericardium Present 4E
TS22: intraembryonic coelom Present Regionally restricted 4E
TS22: heart Present Regionally restricted 4E Expression is in the sinus horn mesenchyme.
Specimen 4F: embryonic day 10.5; Tbx18tm2Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 4F Expression is the same as in wild-type embryos.
TS17: visceral pericardium Present 4F Expression is the same as in wild-type embryos.
TS17: intraembryonic coelom Present Regionally restricted 4F Expression is the same as in wild-type embryos.
TS17: sinus venosus Present Regionally restricted 4F Expression is the same as in wild-type embryos.
Specimen 4G: embryonic day 11.5; Tbx18tm2Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present 4G Expression is the same as in wild-type embryos.
TS19: visceral pericardium Present 4G Expression is the same as in wild-type embryos.
TS19: intraembryonic coelom Present Regionally restricted 4G Expression is the same as in wild-type embryos.
TS19: sinus venosus Present Regionally restricted 4G Expression is the same as in wild-type embryos.
Specimen 4H: embryonic day 12.5; Tbx18tm2Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 4H Expression is the same as in wild-type embryos.
TS20: visceral pericardium Present 4H Expression is the same as in wild-type embryos.
TS20: intraembryonic coelom Present Regionally restricted 4H Expression is the same as in wild-type embryos.
TS20: sinus venosus Present Regionally restricted 4H Expression is the same as in wild-type embryos.
Specimen 4I: embryonic day 13.5; Tbx18tm2Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS21: cardiac muscle tissue Present 4I Expression is the same as in wild-type embryos.
TS21: visceral pericardium Present 4I Expression is the same as in wild-type embryos.
TS21: intraembryonic coelom Present Regionally restricted 4I Expression is the same as in wild-type embryos.
Specimen 4J: embryonic day 14.5; Tbx18tm2Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Present 4J Expression is the same as in wild-type embryos.
TS22: visceral pericardium Present 4J Expression is the same as in wild-type embryos.
TS22: intraembryonic coelom Present Regionally restricted 4J Expression is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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