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Gene Expression Data
Assay Details
Assay
Reference: J:86964 Andrieu D, et al., Expression of the Prader-Willi gene Necdin during mouse nervous system development correlates with neuronal differentiation and p75NTR expression. Gene Expr Patterns. 2003 Dec;3(6):761-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5700180
Gene symbol: Ndn
Gene name: necdin, MAGE family member
Antibody: anti-Necdin (NC243)
Detection system: Secondary antibody
Results
Specimen 1N: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: diencephalon Present Widespread 1N
TS25: suprachiasmatic nucleus Present 1N
TS25: cortical subplate Present 1N
TS25: cerebral cortex Present Regionally restricted 1N Expression in mid-cortical layers of dorsal cortex.

Specimen E17 not shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: hindbrain Present

Specimen 1P: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cortical subplate Present 1P
TS27: cerebral cortex marginal zone Weak 1P

Specimen 1Q: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb Present Regionally restricted 1Q Persistent expression in specific neuronal populations.

Specimen P0-P2 not shown: postnatal day 0-2 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present Authors report expression in the cerebellum, hippocampus and other specific neural structures.
TS27: hippocampus Present Authors report expression in the cerebellum, hippocampus and other specific neural structures.

Specimen P7 not shown: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Expression declines in the cortex.

Specimen adult not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hindbrain Present Expression limited to discrete areas, in particular the hypothalamus, thalamus and hinbrain.
TS28: hypothalamus Present Expression limited to discrete areas, in particular the hypothalamus, thalamus and hinbrain.
TS28: thalamus Present Expression limited to discrete areas, in particular the hypothalamus, thalamus and hinbrain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory