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Tg(Six1-cre)2Kwk
Transgene Detail
Summary
Symbol: Tg(Six1-cre)2Kwk
Name: transgene insertion 2, Kiyoshi Kawakami
MGI ID: MGI:5700048
Synonyms: mSix1-8-NLSCre, Six1enh8-Cre, Tg(Six1-enh8-cre)2Kwk
Transgene: Tg(Six1-cre)2Kwk  Location: unknown  
Alliance: Tg(Six1-cre)2Kwk page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Six1-cre)2Kwk expression driven by 1 gene
 
Mutation detailsThe transgene contains the sensory ganglion-specific enhancer of the Six1 homeobox gene (Six1enh8), the HSV thymidine kinase gene promoter, a chimeric intron a cre recombinase gene with a nuclear localization signal that are flanked by two tandem copies of the core region of the HS4 insulator. Lines 22L, 30L, 31L, 32L, 33L, 7l and 35l were generated. Line 35l is also designated as line 2 and was selected as the representative line. (J:227250)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Six1 (species not specified)
Summary of all recombinase alleles driven by Six1.
User Notes:
 Additional information submitted by the research community
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:227250 Sato S, et al., Activation of Six1 Expression in Vertebrate Sensory Neurons. PLoS One. 2015;10(8):e0136666
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory