Tg(Pdgfrb-rtTA)58Gpta
Transgene Detail
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Symbol: |
Tg(Pdgfrb-rtTA)58Gpta |
Name: |
transgene insertion 58, Rana Gupta |
MGI ID: |
MGI:5699270 |
Synonyms: |
PdgfrbetartTA |
Transgene: |
Tg(Pdgfrb-rtTA)58Gpta Location: unknown
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Alliance: |
Tg(Pdgfrb-rtTA)58Gpta page
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Transgene Type: |
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Transgenic (Transactivator) |
Mutation: |
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Insertion
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Mutation details: The RP23-304O21 bacterial artificial chromosome (BAC) containing exons 1-2 of the platelet derived growth factor receptor, beta polypeptide (Pdgfrb) gene and 10 kb of upstream regulatory sequence was obtained. This BAC was modified by replacing the Pdgfrb start codon in exon 2 with an rtTA (reverse tetracycline-regulated transactivator) sequence and a polyadenylation sequence. No other genes are encoded by this BAC.
(J:226969)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:226969 Vishvanath L, et al., Pdgfrbeta+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. Cell Metab. 2016 Feb 9;23(2):350-9 |
All: |
9 reference(s) |
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