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Tg(Pdgfrb-rtTA)58Gpta
Transgene Detail
Summary
Symbol: Tg(Pdgfrb-rtTA)58Gpta
Name: transgene insertion 58, Rana Gupta
MGI ID: MGI:5699270
Synonyms: PdgfrbetartTA
Transgene: Tg(Pdgfrb-rtTA)58Gpta  Location: unknown  
Alliance: Tg(Pdgfrb-rtTA)58Gpta page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe RP23-304O21 bacterial artificial chromosome (BAC) containing exons 1-2 of the platelet derived growth factor receptor, beta polypeptide (Pdgfrb) gene and 10 kb of upstream regulatory sequence was obtained. This BAC was modified by replacing the Pdgfrb start codon in exon 2 with an rtTA (reverse tetracycline-regulated transactivator) sequence and a polyadenylation sequence. No other genes are encoded by this BAC. (J:226969)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:226969 Vishvanath L, et al., Pdgfrbeta+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. Cell Metab. 2016 Feb 9;23(2):350-9
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory