Tg(Ins1-HIST1H2BB/mCherry)5091Mhsg
Transgene Detail
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| Symbol: |
Tg(Ins1-HIST1H2BB/mCherry)5091Mhsg |
| Name: |
transgene insertion 5091, Mark Huising |
| MGI ID: |
MGI:5698910 |
| Synonyms: |
mIns1-H2b-mCherry |
| Transgene: |
Tg(Ins1-HIST1H2BB/mCherry)5091Mhsg Location: unknown
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| Alliance: |
Tg(Ins1-HIST1H2BB/mCherry)5091Mhsg page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgene was designed with the murine insulin I (Ins1) promoter driving expression of an H2B-mCherry fusion protein (coding sequence for the human HIST1H2BB gene [histone 1 H2bb] with a C-terminal monomeric red fluorescent protein sequence). The founder was determined to transmit the transgene to approximately 75% of F1 offspring, indicative of 2 independent transgene insertion sites. One of these sites was subsequently determined to be silent and was bred out. Nuclear-localized mCherry fluorescence is observed in all pancreatic beta cells. Fluorescence is not seen in any other cells.
(J:214617)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:214617 Benner C, et al., The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression. BMC Genomics. 2014;15:620 |
| All: |
5 reference(s) |
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Analysis Tools
