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Gene Expression Data
Assay Details
Assay
Reference: J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698423
Gene symbol: Prkaa1
Gene name: protein kinase, AMP-activated, alpha 1 catalytic subunit
Results
Specimen 2D: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 2D Expression barely detectable above background levels. Authors report expression confined mainly to the neuropil.
TS28: hippocampus pyramidal cell layer Present Regionally restricted 2D Low but detectable levels of expression in soma of pyramidal cells.

Specimen 3B: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 3B Authors report expression confined to neuropil. Low but detectable levels of expression in soma of cerebellar neurons.

Specimen 4B: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Ambiguous 4B Authors report expression was not much above background except in glomeruli.

Specimen 5A: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted 5A Expression in neuropil, including axons cut in cross section, and at a lower level in motor neurons.

Specimen Table 1: postnatal (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Regionally restricted Low levels of expression in soma of cortical neurons. No expression in astrocytes.
TS28: hippocampus pyramidal cell layer Present Regionally restricted Expression in pyramidal neurons. No expression in astrocytes.
TS28: cerebellum Purkinje cell layer Present Regionally restricted Expression in granule cells and Purkinje cells. No expression in astrocytes.
TS28: cerebellum granule cell layer Present Regionally restricted Expression in granule cells and Purkinje cells. No expression in astrocytes.
TS28: spinal cord Trace Regionally restricted Barely detectable expression in motor neurons. No expression in astrocytes.
TS28: facial nucleus Ambiguous Not detectable to low expression in motor neurons.
TS28: main olfactory bulb Absent No expression in mitral, granule or periglomerular cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory