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Gene Expression Data
Assay Details
Assay
Reference: J:217589 Kawakami E, et al., The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators. Mech Dev. 2015 Feb;135:31-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698136
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A Fbxl11+/-: embryonic day 10.5; Kdm2atm1d(KOMP)Mtok/Kdm2a+ (more )
Structure Level Pattern Image Note
TS17: telencephalon Absent 4A CC3 Fbxl11 +/-
Specimen 4A Fbxl11-/-: embryonic day 10.5; Kdm2atm1d(KOMP)Mtok/Kdm2atm1d(KOMP)Mtok (more )
Structure Level Pattern Image Note
TS17: telencephalon Present 4A CC3 Fbxl11 -/- Proportion of expressing cells was dramatically elevated in homozygous mutant neocortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory