Col10a1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:213921 Yang L, et al., Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12097-102
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5697920
Gene symbol:	Col10a1
Gene name:	collagen, type X, alpha 1

Reporter:	GFP
Antibody:	anti-GFP (ab6556)

Results

Specimen 1E left: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: tibia	Present	Regionally restricted	1E Col10a1-GFP	Expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone. No expressing cells are seen in the perichondrium/periosteum.
TS28: hypertrophic cartilage zone	Present		1E Col10a1-GFP	Expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone. No expressing cells are seen in the perichondrium/periosteum.

Specimen 1E left inset: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: vertebra	Present	Regionally restricted	1E Col10a1-GFP inset	Expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.
TS28: hypertrophic cartilage zone	Present		1E Col10a1-GFP inset	Expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.

Specimen S2 Scapula left: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: scapula	Present	Regionally restricted	S2_Scapula Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.
TS28: hypertrophic cartilage zone	Present		S2_Scapula Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.

Specimen S2 Rib left: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: rib	Present	Regionally restricted	S2_Rib Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.
TS28: hypertrophic cartilage zone	Present		S2_Rib Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.

Specimen S2 Calvaria left: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: chondrocranium	Absent		S2_Calvaria Col10a1-GFP	No expression is seen in intramembranous bones.

Specimen S2 inset left: postnatal day 10; Col10a1^tm4Ksec/Col10a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: mandible condylar process	Present	Regionally restricted	S2_inset Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.
TS28: hypertrophic cartilage zone	Present		S2_inset Col10a1-GFP	In endochondral bones, expression is restricted to the hypertrophic chondrocytes in the hypertrophic zone.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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